Small bowel obstruction in Peutz Jeghers syndrome: case report

  • Abdelhak E Medicine and Pharmacy of Casablanca, Visceral Emergency Department P35, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
  • Khalid J Medicine and Pharmacy of Casablanca, Visceral Emergency Department P35, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
  • Mosaab E Medicine and Pharmacy of Casablanca, Visceral Emergency Department P35, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
  • Khadija K Medicine and Pharmacy of Casablanca, Visceral Emergency Department P35, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
  • Abdessamad M Medicine and Pharmacy of Casablanca, Visceral Emergency Department P35, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
  • Mounir B Medicine and Pharmacy of Casablanca, Visceral Emergency Department P35, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
  • Abdelilah E Medicine and Pharmacy of Casablanca, Visceral Emergency Department P35, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
  • Khalid E Medicine and Pharmacy of Casablanca, Visceral Emergency Department P35, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
  • Khaleq K Medicine and Pharmacy of Casablanca, Visceral Emergency Department P35, IBN ROCHD University hospital of Casablanca, Casablanca, Morocco
Keywords: Peutz-Jeghers syndrome, Hamartomatous polyp, Intussusception, Small bowel obstruction

Abstract

Introduction: Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant congenital disorder characterised by the presence of hamartomatous polyps in the gastrointestinal tract and mucocutaneous lentiginosis. It is associated with an elevated risk of cancer and substantial morbidity related to polyps, notably intestinal intussusception during childhood.

Case report: We report the case of a 32-year-old man patient, who consulted for subocclusif syndrome with multiple pigmented spots on the face and lips. Abdominal computed tomography (CT) revealed an image of jejuno-jejunal intussusception and substenotic jejunal mass. The patient underwent a double-segmental small bowel resection, removing the intussusception and the jejunal mass. The pathologic examination confirmed the diagnosis of Peutz-Jeghers polyps with moderately differentiated, invasive adenocarcinoma.

Discussion: The diagnosis of SPJ can be established in patients presenting one or more polyps and at least two of the associated clinical criteria: labial melanin deposits, family history of the syndrome and polyposis of the small bowel. Half of the cases present with small bowel obstruction. PJS is associated with an increased risk of gastrointestinal and non-gastrointestinal malignancies. Endoscopic or surgical polypectomy remains the preferred treatment option to prevent complications.

Conclusion: Regular surveillance of the gastrointestinal tract is recommended both for cancer prevention and early detection, and to prevent polyp-related complications, and certainly improve prognosis in these patients.

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How to Cite
1.
Abdelhak E, Khalid J, Mosaab E, Khadija K, Abdessamad M, Mounir B, Abdelilah E, Khalid E, Khaleq K. Small bowel obstruction in Peutz Jeghers syndrome: case report. Int J Med Res Rev [Internet]. 2025Jul.19 [cited 2025Jul.22];13(2):46-1. Available from: https://www.ijmrr.medresearch.in/index.php/ijmrr/article/view/1551
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Vol 13 No 2 (2025): Apr-Jun
Section
Case Report

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